קלנג שמואל, ד”ר

דרגה ותפקיד: מרצה (נלווה) מומחה
כתובת דוא״ל: mklang100@gmail.com
שעות קבלה: בתיאום מראש
חדר: חדר 411, קומה 4, בניין הפקולטה למדעי הרווחה והבריאות
שייכות לחוג / ביה”ס / יחידה:
ביה”ס לבריאות הציבור
תחומי מחקר: הערכת טכנולוגיות, סל הבריאות, סל התרופות
CRIS
 
שמוליק קלנג

Background

  • Progressive leadership experience in large healthcare organizations from pharmacy operations oversight to strategic planning, business development, reimbursement, technology assessment and supply chain optimization.

  • Successful track record in developing new programs and services from conceptualization to launch.

Employment History

  • Meuhedet Health Service  2018-2022
  • Rhenium-Oncotest 2022-2023
    • Head of Early Detection Division
  • Hepacure-Pharma Ltd. 2024-present
    • Chief Executive Officer 

Publications

  1. H. Klang, J. Frucht-Pery, A. Hoffman, and S. Benita. Physicochemical characterization and acute toxicity evaluation of a positively-charged submicron emulsion vehicle. J. Pharm. Pharmacol. 46:986-993, 1994 .
  1. H. Klang, Baszkin A., and S. Benita. The stability of piroxicam incorporated in a positively-charged submicron emulsion for ocular administration. Int. J. Pharm. 132;33-44, 1996 .
  1. KLANG SH; SIGANOS CS; BENITA S; FRUCHTPERY J. PIROXICAM POSITIVELY-CHARGED EMULSION PROTECTS AGAINST CORNEAL ALKALIBURN IN A RABBIT MODEL. Investigative ophthalmology & visual science. issue: 3, vol. 3 : 364 – 364, 1996.
  1. H. Klang, M. Parnas and S. Benita. Emulsions as drug carriers-possibilities, limitations and future perspectives. In: Emulsions and nanosuspensions for the formulation of poorly soluble drugs. R.H. Muller, S. Benita and B. Bohm eds., Medpharm scientific publishers, Stuttgart. . 1998.
  1. H. Klang and S. Benita. Design and evaluation of submicron emulsions as colloidal drug carriers for intravenous administration. In: Submicron emulsions in drug targeting and delivery. S. Benita ed., Harwood academic publishers, The Netherlands. 1999.
  1. H. Klang, C.S. Siganos, S. Benita, and J. Frucht-Pery.. Evaluation of a positively- charged submicron emulsion of piroxicam on the rabbit corneum healing process following alkali burn. J. Control. Rel. 57:19-27, 1999.
  1. BenEzra, S.H. Klang, G. Maftzir, and S. Benita. Submicron emulsions and their effect on corneal cells in vitro. (Submitted for publication)
  1. H. Klang, G. Slama, I. Ringel, A. Kaplun, Y. Talmon and S. Benita. The microstructure of a positively-charged submicron emulsion emulsion. (Submitted for publication).
  1. Klang S, Abdulrazik M., and Benita S. indomethacin ocular tissue distribution. Influence of emulsion droplet surface charge on Pharm Dev Technol. 5(4):521-32, 2000 .
  1. Klang S., Lieberman N., Porath A., Peterburg Y. Reimbursed drug regulation: Comparing two models for control drugs consumption in Israel using permeation coefficient parameter. The Third Annual European Conference of the International Society for Pharmacoeconomics and Outcome Research (ISPOR), November 2000, Antwerp, Belgium.
  1. Giveon S.M., Liberman N., Klang S., Kahan E. Are people who use “natural drugs” aware of their potentially harmful side effects and reporting to family physician? Patient Education and Counseling 53, 5-11, 2004
  1. Ariel Hammerman, Jacob Dreiher, Shmuel H. Klang, Hanan Munitz, Arnon D. Cohen and Margalit

          Goldfracht. Antipsychotics and  diabetes:  an  age-related  association  study.Annals of Pharmacotherapy 42: 1316-1322, : 2008.

  1. Zohar Levi , MD , Paul Rozen, Rachel Hazazi, Alex Vilkin , Amal Waked , Eran Maoz , Shlomo Birkenfeld , Nicky Lieberman, Shmuel Klang , Yaron Niv. Sensitivity, but not Specificity of a Quantitative Immunochemical Fecal Occult Blood for Neoplasia, is Slightly Increased by Low Dose Aspirin, NSAIDS and Anti Coagulants Use. The American Journal of GASTROENTEROLOGY, 17 March 2009.
  1. A Hammerman, SH Klang, N Liebermann. REAL LIFE TREATMENT DURATION OF SORAFENIB OR SUNITINIB IN FIRST LINE METASTATIC RENAL CELL CARCINOMA PATIENTS— A COMPARATIVE ANALYSIS. Value in Health, Vol. 12, Issue 7, A260 October, 2009
  1. 15. Nitzan, M. Low, I. Lavi, A. Hammerman, S. Klang, R. Raz. Variability in Outpatient Antimicrobial Consumption in Israel. Infection 2010; 38: 12–18
  1. Shmuel H. Klang, PhD, Ariel Hammerman, PhD, Nicky Liebermann, MD, Noa Efrat, MD, Julie Doberne, BS, John Hornberger, MD. Economic Implications of 21-Gene Breast Cancer Risk Assay from the Perspective of an Israeli-Managed Health-Care Organization. Value In Health 13 (4), 337–508 , 15 APR 2010
  1. Stemmer, SM; Klang, SH; Ben-Baruch, N; Geffen, DB; Steiner, M; Soussan-Gutman, L; Merling, S; Svedman, C; Rizel, S; Lieberman, N. The impact of the 21-gene Recurrence Score assay on clinical decision-making in node-positive (up to 3 positive nodes) estrogen receptor-positive breast cancer patients. Breast Cancer Res Treat. Jul; 140(1): 83–92, 2013.

     18. Klang, Shmuel H. a; Ben-Amnon, Yuval b; Cohen, Yaeli a; Barak, Yoram. Community pharmacists’ support improves antidepressant adherence in the community. Int Clin Psychopharmacol. 2015 Nov;30(6):316-9.

      19.  Clinical Outcomes in Patients with Node-negative Breast Cancer Treated Based on the Recurrence Score Results: Evidence from a Large Prospectively-designed Registry” by Salomon Stemmer, Mariana Steiner, Shulamith Rizel, Lior Soussan-Gutman, Noa Ben Baruch, Avital Bareket-Samish, David Geffen, Bella Nisenbaum, Kevin Isaacs, Georgeta Fried, Ora Rosengarten, Beatrice Uziely, Christer Svedmann, Debbie  McCullough, Tara Maddala, Shmuel Klang, Jamal Zidan, Larisa Ryvo, Bella Kaufman, Ella Evron, Natalya Karminsky, Hadassah Goldberg, Steven Shak, and Nicky Liebermann. npj Breast Cancer In press